The Legend of Zelda and Metal Gear Solid all the way! 
Both series saw their birth shortly after I was born myself (84) so they've literally accompanied me throughout my lifetime.
The legend of Zelda was first released in 1986 while Metal Gear saw the light of day in 1987.
Ever since then both series have established a leadership position in their genres as they have literally invented the respective styles of narration and gameplay.
Over two decades later, these are the games that I always anticipate most anxiously
.
Per Wikipedia, as of 2010 the Zelda series has sold over 59 million copies, while the Metal Gear series has sold over 27 million copies.
Best,
Filip